A new type of water-soluble fluorescent boronic acid suitable for construction of polyboronic acids for carbohydrate recognition

作者：Yang WQ; Li L; Wang BH^*

来源：Heterocyclic Communications, 2004, 10(6): 383-388.

In this paper we report boronic acid 1 with a quinoline moiety as a new type of fluorescent probe for carbohydrates, which shows significant fluorescence intensity increases upon sugar binding at physiological pH. This compound has the unique structural feature of separating the boronic acid moiety from the presumed fluorophore, and is ready for the construction of polyboronic acids through tethering to its carboxylic group for high selectivity and affinity recognition of carbohydrates of biological interest.

• 出版日期2004