A novel mutation in KNOPF uncovers the role of alpha-glucosidase I during post-embryonic development in Arabidopsis thaliana

作者：Furumizu Chihiro; Komeda Yoshibumi^*

来源：FEBS Letters, 2008, 582(15): 2237-2241.

DOI：10.1016/j.febslet.2008.05.019

• epidermal development
• KNOPF/GLUCOSIDASE 1
• N-glycan processing
• alpha-Glucosidase I
• Arabidopsis thaliana

N-glycosylation is a common protein modification. Joining of polypeptide and carbohydrate elements into hybrid molecules provides an opportunity to fine-tune protein properties. However, the role of N-glycosylation on the development of multicellular organisms remains elusive. Here we report a hypomorphic allele of KNOPF/GLUCOSIDASE 1, which allows us to describe the effects of impaired alpha-glucosidase I on post-embryonic development of plants for the first time. This knf-101 mutation alters cell shape but does not affect cell arrangements, except for the patterning of specialized epidermal cells, delineating the significance of N-glycan processing during epidermal development in Arabidopsis.

• 出版日期2008-6-25