Adjustable Hyperthermia Response of Self-Assembled Ferromagnetic Fe-MgO Core-Shell Nanoparticles by Tuning Dipole-Dipole Interactions

作者：Martinez Boubeta Carlos^*; Simeonidis Konstantinos; Serantes David; Conde Leboran Ivan; Kazakis Ioannis; Stefanou George; Pena Luis; Galceran Regina; Balcells Lluis; Monty Claude; Baldomir Daniel; Mitrakas Manassis; Angelakeris Makis

来源：Advanced Functional Materials, 2012, 22(17): 3737-3744.

DOI：10.1002/adfm.201200307

• magnetic hyperthermia
• ferromagnetic nanoparticles

The Fe-MgO core-shell morphology is proposed within the single-domain nanoparticle regime as an enhanced magnetically driven hyperthermia carrier. The combinatory use of metallic iron as a core material together with the increased particle size (3765 nm) triggers the tuning of dipolar interactions between particles and allows for further enhancement of their collective heating efficiency via concentration control. A theoretical universal estimation of hysteresis losses reveals the role of dipolar interactions on heating efficiency and outlines the strong influence of coupling effects on hyperthermia opening a novel roadmap towards multifunctional heat-triggered theranostics particles.

• 出版日期2012-9-11