Aripiprazole salts. III. Bis(aripiprazolium) oxalate-oxalic acid (1/1)

作者：Freire Eleonora^*; Polla Griselda; Baggio Ricardo

来源：Acta Crystallographica Section C-Crystal Structure Communications, 2013, 69(2): 186-+.

DOI：10.1107/S0108270113001133

The asymmetric unit of the title salt [systematic name: bis(4-(2,3-dichlorophenyl)-1-{4-[(2-oxo-1,2,3,4-tetrahydroquinolin-7-yl)oxy]butyl}piperazin-1-ium) oxalate-oxalic acid (1/1)], 2C(23)H(28)Cl(2)N(3)O(2)(+)center dot C2O42-center dot C2H2O4, consists of one protonated aripiprazole unit (HArip(+)), half an oxalate dianion and half an oxalic acid molecule, the latter two lying on inversion centres. The conformation of the HArip(+) cation differs from that in organized into planar ribbons parallel to (01 (2) over bar). The oxalate anions and oxalic acid molecules form hydrogen-bonded chains running along [010], which 'pierce' the planar ribbons, interacting with them through a number of stronger N-H center dot center dot center dot O and weaker C-H center dot center dot center dot O hydrogen bonds, forming a three-dimensional network.

• 出版日期2013-2