科研之友
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摘要
Under the assumption that the incidence rate of the infection and the removal rate of the infective by cytotoxic T lymphocytes are nonlinear, we study the global dynamics of a HIV infection model with the response of the immune system using characteristic equation, the Fluctuation lemma, and the direct Lyapunov method. The existence of a threshold parameter, i.e., the basic reproduction number or basic reproductive ratio is established and the global stability of the equilibria is discussed.
