Antiangiogenic Activity of Flavonoids from Melia azedarach

作者:Kumazawa Shigenori*; Kubota Satomi; Yamamoto Haruna; Okamura Naoki; Sugiyama Yasumasa; Kobayashi Hirokazu; Nakanishi Motoyasu; Ohta Toshiro
来源:Natural Product Communications, 2013, 8(12): 1719-1720.

摘要

Three flavonoid glycosides, 1 (rutin: quercetin 3-O-rutinoside), 2 (kaempferol 3-O-robinobioside) and 3 (kaempferol 3-O-rutinoside) were isolated from the subcritical water extracts of Melia azedarach leaves. Strong antiangiogenic activity of these compounds was observed in the in vivo assay using the chorioallantoic membrane (CAM) from growing chick embryos.

  • 出版日期2013-12