Association of carotid intima media thickness with blood pressure and HDL cholesterol in children

作者：Arnaiz Pilar; Villarroel Luis; Barja Salesa; Godoy Ivan; Cassis Berta; Dominguez Angelica; Castillo Oscar; Farias Marcelo; Carvajal Jacqueline; Cristina Tinoco Ana; Mardones Francisco^*

来源：Revista Medica de Chile, 2012, 140(10): 1268-1275.

DOI：10.4067/S0034-98872012001000005

• Blood pressure
• Carotid Intima-Media thickness
• Child
• Cholesterol HDL

Background: Cardiovascular risk factors must be controlled since childhood. Aim: To assess the association of carotid intima media thickness (CIMT) with the components of the metabolic syndrome in Children. Material and Methods: Cross sectional assessment of 299 children aged 11.5 +/- 0.9 years (58% women) with and without metabolic syndrome components. Anthropometric parameters and blood pressure were measured and a blood sample was obtained to measure blood glucose and lipids. CIMT was measured using high resolution ultrasound. Results: Ninety three percent of children were post puberal, 64% were overweight and 25% had metabolic syndrome. Mean and maximum CIMT correlated with systolic blood pressure (r = 0.21 and 0.21 respectively p %26lt; 0.01). Children with a CIMT over the 75th percentile had higher blood pressure and lower HDL cholesterol. A stepwise logistic regression accepted both variables as predictors of CIMT with odds ratios for mean CIMT of 1.46 (1.19-1-79) and 0.81 (0.7-0.94) per five units of change, respectively. Conclusions: In this group of children systolic blood pressure and HDL cholesterol are associated to CIMT. (Rev Med Chile 2012; 140: 1268-1275).

• 出版日期2012-10