Nitrogen-bridged heterocycles via cycloaddition of non-classical heterocyclic-fused-[c]thiazoles

作者:Soares Maria I L; Gomes Clara S B; Pinho e Melo Teresa M V D
来源:Tetrahedron, 2011, 67(43): 8392-8403.
DOI:10.1016/j.tet.2011.08.001

摘要

The [4 pi+2 pi] cycloaddition of non-classical heterocyclic-fused-[c]thiazoles was explored allowing the synthesis of a range of new nitrogen-bridged bi-, tri- and tetracyclic heterocyclic compounds namely, pyrazolo[1,5-a]pyridines, thiazolo[2,3,4-cd]pyrrolizines and indolizines. For the first time, one non-classical pyrrolo[1,2-c]thiazole was isolated and its structure determined by X-ray crystallography.

  • 出版日期2011-10-28