Anti-angiogenic activity of the methanol extract and its fractions of Ulmus davidiana var. japonica

作者：Jung Hyun Joo; Jeon Hye Jin; Lim Eun Ju; Ahn Eun Kyoung; Song Yun Seon; Lee Sanghyun; Shin Kuk Hyun; Lim Chang Jin; Park Eun Hee^*

来源：Journal of Ethnopharmacology, 2007, 112(2): 406-409.

DOI：10.1016/j.jep.2007.03.006

• Ulmus davidiana var. japonica
• angiogenesis
• anti-angiogenic
• chorioallantoic membrane
• Ulmaceae

This study aimed to elucidate anti-angiogenic activity of Ulmus davidiana var. japonica that has been widely used in folk medicine. The methanol extract (UDE) of Uhnus davidiana var. japonica concentration-dependently displayed a strong inhibition in the chick chorioallantoic membrane (CAM) angiogenesis. The n-butanol fraction of UDE and subsequent 30% MeOH subtraction were identified to be most responsible for the anti-angiogenic activity.

• 出版日期2007-6-13