A RARE Hb H DISEASE DUE TO THE - -(SEA) AND 16.6 kb alpha-THALASSEMIA-2 DELETIONS

作者：Sroymora Suravee; Jindadamrongwech Sumalee^*; Butthep Punnee; Chuncharunee Su****

来源：Hemoglobin, 2012, 36(2): 200-204.

DOI：10.3109/03630269.2012.655355

• Hb H disease
• 16.6 kb Deletion
• alpha-Thalassemia (alpha-thal)

A large deletional alpha-thalassemia-2 (alpha-thal-2) allele was identified in a Thai woman with Hb H disease. The proband has alpha-thal-1 (SEA type) in conjunction with a 16.6 kb deletion affecting the alpha 2-globin allele. The proband had severe anemia and required a blood transfusion during puerperium.

• 出版日期2012