科研之友
微信
新浪微博
Facebook
分享链接
摘要
A one-pot, three-component condensation of aldehydes, 2-naphthol and 2-aminobenzothiazole in the presence of multi-SO3H functionalized ionic liquid (synthesized from hexamethylenetetramine and 1,4-butane sulfonate), as an effective catalyst for the synthesis of 1-(benzothiazolylamino)methyl-2-naphthol derivatives, under thermal and solvent-free conditions, is described. These products involve two biologically active parts; Betti's base and benzothiazole. The present methodology offers several advantages, such as good yields, short reaction times, and easy work-up. The catalyst could be recycled and reused without substantial reduction in its catalytic activities.
- 出版日期2014-6
