Utility of endoscopic ultrasound-guided transbronchial fine-needle cytology in the diagnosis of sarcoidosis: A Saudi experience

作者：Raddaoui Emad^*; Alhamad Esam H; Zaidi Shaesta Naseem; Arafah Maha; AlHabeeb Fatmah Fahad

来源：Cytojournal, 2014, 11(1): 31.

DOI：10.4103/1742-6413.146118

• Endoscopic ultrasound-guided transbronchial fine-needle cytology
• mediastinal lymph nodes
• sarcoidosis

Background: Endoscopic ultrasound-guided transbronchial fine-needle aspiration (EBUS-TFNA) is a minimally invasive technique for diagnosis of mediastinal masses/lesions. Although most studies have reported the utility of EBUS-TFNA in malignancy, its use has been extended to the benign conditions as well. Objective: The present study focused on utility of EBUS in contributing to reach the final diagnosis of sarcoidosis. Design: From May 2010 to December 2013, 19 of 80 patients who underwent EBUS-TFNA at one center for radiologically suspicious lesions for sarcoidosis, and with no definite histological diagnosis, were included in this retrospective study. Results: When the histological diagnosis was taken as the gold standard, the sensitivity of EBUS-TFNA was 84.2% and specificity 100% with the positive predictive value of 100. The combined diagnostic sensitivity of EBUS-TFNA and transbronchial lung biopsy was 100%. Conclusion: EBUS is a valuable, minimally invasive diagnostic modality to support the diagnosis of sarcoidosis in appropriate clinical setting, after conventional work-up - particularly if patients have suspicious radiological findings. This minimally invasive procedure helps in providing a final diagnosis without exposing the patient to the risk of complications from more invasive procedures.

• 出版日期2014-12-3