A corneal elastic dynamic model derived from Scheimpflug imaging technology

作者:Shih Po Jen; Cao Huei Jyun; Huang Chun Ju; Wang I Jong; Shih Wen Pin; Yen Jia Yush*
来源:Ophthalmic and Physiological Optics, 2015, 35(6): 663-672.
DOI:10.1111/opo.12240

摘要

PurposeTo simultaneously extract the corneal Young's modulus and the damping ratio from Scheimpflug imaging data. MethodsA spherical diaphragm model can better represent the geometry and physics of an eyeball than the popular mass-spring-damper model. This research derived the dynamic model of a water-filled spherical diaphragm based on the hydrodynamics and wave propagation theories. By applying modal analysis on the model, one can decouple the cornea vibration into individual modes and reconstruct the air puff vibration from the decoupled responses. By matching this response with the Scheimpflug imaging data from the Corvis((R)) ST, it was then possible to extract multiple physiological properties as desired. ResultsThe dynamic modal analysis was employed to extract the corneal physiological properties of 25 Taiwanese normal subjects. Specifically, the corneal Young's moduli and damping ratios were estimated. In fact the model is dependent on the physiological parameters such as cornea thickness, densities, and intraocular pressure. It is thus also possible to extract these parameters through multi-goal minimisation processes. ConclusionsThe spherical diaphragm model was able to better describe the dynamic response of the eyeball. The model analysis also provides additional corneal physiological properties that were not available through other means.

  • 出版日期2015-11