Autoimmune polyendocrine syndrome type I and brain calcinosis

作者：Abraham Alon^*; Ziv Ilan; Steinmetz Adam; Groshar David; Djaldetti Ruth

来源：Parkinsonism & Related Disorders, 2010, 16(2): 101-104.

DOI：10.1016/j.parkreldis.2009.07.014

• Autoimmune polyendocrine syndrome type I
• Brain calcinosis
• Parkinsonism

Autoimmune polyendocrine syndrome (APS) is a rare disorder. One of the possible associated endocrinopathies in APS is hypoparathyroidism. We describe brain calcifications secondary to hypoparathyroidism in family members with APS and compare clinical manifestations, the extent of brain calcifications on CT scans and the result of PET-FDG scans. We found extensive brain calcifications and striatal hypometabolism in PET-FDG scan in the only symptomatic member of the family, which supports the assumption that extensive brain calcification and the presence of hypometabolism in PET-FDG scan are likely to be found in symptomatic patients with brain calcifications.

• 出版日期2010-2