Acute effect of high-intensity cycling exercise on carotid artery hemodynamic pulsatility

作者：Babcock Matthew C; Lefferts Wesley K; Hughes William E; Fitzgerald Kimberly L; Leyer Briana K; Redmond Jessica G; Heffernan Kevin S^*

来源：European Journal of Applied Physiology, 2015, 115(5): 1037-1045.

DOI：10.1007/s00421-014-3084-6

• Hemodynamic pulsatility
• Wave intensity analysis
• Exercise
• Arterial stiffness
• Wave reflection

Investigate the effects of acute high-intensity exercise on common carotid artery (CCA) dimensions, stiffness, and wave intensity.
Fifty-five healthy men and women (22 +/- A 5 year; 24.5 +/- A 2.7 kg m(-2)) underwent 30 s of high-intensity cycling (HIC; Wingate anaerobic test). CCA diameter, stiffness [beta-stiffness, Elastic Modulus (E (p))], pulsatility index (PI), forward wave intensities [due to LV contraction (W (1)) and LV suction (W (2))], and reflected wave intensity [negative area (NA)] were assessed using a combination of Doppler ultrasound, wave intensity analysis, and applanation tonometry at baseline and immediately post-HIC.
CCA beta-stiffness, E (p), PI and pulse pressure increased significantly immediately post-HIC (p < 0.05). CCA diameter decreased acutely post-HIC (p < 0.05). There were also significant increases in W (1) and NA and a significant decrease in W (2) (p < 0.05). A significant correlation was found between change in W (1) and PI (r = 0.438, p < 0.05), from rest to recovery as well as a significant inverse correlation between W (2) and PI (r = -0.378, p < 0.05). Change in PI was not associated with change in CCA stiffness or NA (p > 0.05).
Acute HIC results in CCA constriction and increases in CCA stiffness along with increases in hemodynamic pulsatility. The increase in pulsatility may be due to a combination of increased forward wave intensity from increased LV contractility into a smaller vessel (i.e. impaired matching of diameter and flow) coupled with reduced LV suction.

• 出版日期2015-5