Microchip capillary electrophoresis instrumentation for in situ analysis in the search for extraterrestrial life

作者：Mora Maria F; Stockton Amanda M; Willis Peter A^*

来源：Electrophoresis, 2012, 33(17): 2624-2638.

DOI：10.1002/elps.201200102

• Extraterrestrial exploration
• Laser-induced fluorescence
• Microchip capillary electrophoresis
• Pneumatically actuated valves

The search for signs of life on extraterrestrial planetary bodies is among NASA's top priorities in Solar System exploration. The associated pursuit of organics and biomolecules as evidence of past or present life demands in situ investigations of planetary bodies for which sample return missions are neither practical nor affordable. These in situ studies require instrumentation capable of sensitive chemical analyses of complex mixtures including a broad range of organic molecules. Instrumentation must also be capable of autonomous operation aboard a robotically controlled vehicle that collects data and transmits it back to Earth. Microchip capillary electrophoresis (mu CE) coupled to laser-induced fluorescence (LIF) detection provides this required sensitivity and targets a wide range of relevant organics while offering low mass, volume, and power requirements. Thus, this technology would be ideally suited for in situ studies of astrobiology targets, such as Mars, Europa, Enceladus, and Titan. In this review, we introduce the characteristics of these planetary bodies that make them compelling destinations for extraterrestrial astrobiological studies, and the principal groups of organics of interest associated with each. And although the technology we describe here was first developed specifically for proposed studies of Mars, by summarizing its evolution over the past decade, we demonstrate how mu CE-LIF instrumentation has become an ideal candidate for missions of exploration to all of these nearby worlds in our Solar System.

• 出版日期2012-9