Diagnostic criteria, severity classification and guidelines of localized scleroderma

作者:Asano Yoshihide*; Fujimoto Manabu; Ishikawa Osamu; Sato Shinichi; Jinnin Masatoshi; Takehara Kazuhiko; Hasegawa Minoru; Yamamoto Toshiyuki; Ihn Hironobu
来源:Journal of Dermatology, 2018, 45(7): 755-780.
DOI:10.1111/1346-8138.14161

摘要

We established diagnostic criteria and severity classification of localized scleroderma because there is no established diagnostic criteria or widely accepted severity classification of the disease. Also, there has been no clinical guideline for localized scleroderma, so we established its clinical guideline ahead of all over the world. In particular, the clinical guideline was established by clinical questions based on evidence-based medicine according to the New Minds Clinical Practice Guideline Creation Manual (version 1.0). We aimed to make the guideline easy to use and reliable based on the newest evidence, and to present guidance as specific as possible for various clinical problems in treatment of localized scleroderma.