Microbiological diagnosis of chikungunya virus in Spain (2006-2007): Case detection in travelers

作者：Paz Sanchez Seco Maria; Isabel Negredo Ana; Puente Sabino; Jesus Pinazo Ma; Shuffenecker Isabelle; Tenorio Antonio; Giovanni Fedele Cesare; Domingo Cristina; Miguel Rubio Jose; de Ory Fernando

来源：Enfermedades Infecciosas y Microbiologia Clinica, 2009, 27(8): 457-461.

DOI：10.1016/j.eimc.2008.07.011

• Chikungunya virus
• Imported illness
• Microbiological diagnosis

Introduction: The chikungunya virus is a clear example of an emergent pathogen, as demonstrated by the important outbreaks reported in recent years on some islands in the Indian Ocean, on the Indian subcontinent, and in Italy. The autochthonous outbreak that took place in Europe has shown that the international health authorities were tight in their concern about the possibility that this arbovirus could become established in countries with a temperate climate where the appropriate vectors circulate.
Methods: A total of 308 patients were studied to investigate symptoms consistent with infection by this virus occurring during their stay in, or after their return from, an endemic area. Molecular and/or serological methods were used to seek evidence of infection by chikungunya virus.
Results: Twenty-nine positive cases were diagnosed. The molecular and serological tools are complementary: molecular technology generated positive results at the onset of symptoms and serology provided positive testing in samples with a longer evolution time.
Conclusion: The first cases of infection by chikungunya virus in Spanish travelers have been detected. The tools necessary for correct diagnosis of infection by this virus are available in our country.

• 出版日期2009-10