A convenient synthesis of quinazoline derivatives via cascade imino-Diels-Alder and oxidation reaction

作者：Chen, Xue Ming; Wei, Hui; Yin, Lu; Li, Xing Shu^*

来源：Chinese Chemical Letters, 2010, 21(7): 782-786.

DOI：10.1016/j.cclet.2010.03.003

• Quinazolines
• alpha-Iminoesters
• Imino-Diels-Alder reaction
• CuBr(2)

Quinazoline derivatives were synthesized from alpha-iminoesters via a cascade imino-Diels-Alder and then oxidation reaction catalyzed with CuBr(2). This method provided a new strategy for preparing quinazoline derivatives which may be useful in the synthesis of heterocyclic intermediates.

• 出版日期2010-7
• 单位中山大学