A Facile Route to 4-Polyfluoroarylquinolin-2(1H)-ones and 4-Polyfluoroarylcoumarins via C-H Bond Activation

作者：Fang, Ling; Xue, Lijun; Yang, Peng; Li, Xiaodan; Wang, Zhiyong^*

来源：Chemistry Letters, 2017, 46(8): 1223-1226.

DOI：10.1246/cl.170466

• Polyfluoroarene
• Coumarin
• Quinolin-2(1H)-one

Palladium-catalyzed cross-coupling reaction of 4-trifloxy-quinolin-2(1H)-ones or 4-chlorocoumarins with polyfluoroarenes has been successfully developed. Under mild conditions, the reactions afforded 4-polyfluoroarylquinolin-2(1H)-ones and 4-polyfluoroarylcoumarins, which feature a wide range of bioactive compounds, with good yields.

• 出版日期2017-8
• 单位重庆工商大学; 重庆大学