A Retrospective Study of Q-Switched Alexandrite Laser in Treating Nevus of Ota

作者：Liu, Jia; Ma, Yuan-Ping; Ma, Xiao-Guang; Chen, John Z. S.; Sun, Yan; Xu, Hong-Hui; Gao, Xing-Hua; Chen, Hong-Duo; Li, Yuan-Hong^*

来源：Dermatologic Surgery, 2011, 37(10): 1480-1485.

DOI：10.1111/j.1524-4725.2011.02092.x

• RUBY-LASER
• COMPLICATIONS

BACKGROUND The Q-switched alexandrite laser (QSAL) has been clinically proven to be effective in treating nevus of Ota, but a large-scale retrospective study with long-term follow-up has never been performed. @@@ OBJECTIVE To evaluate the efficacy of the QSAL in treating nevus of Ota, the laser's long-term side effects, complications associated with the treatments, and the recurrence rate. @@@ MATERIALS AND METHODS Eight hundred six patients (651 female, 155 male) with a diagnosis of nevus of Ota who had received a series of QSAL (wavelength 755 nm) treatments were recruited. The typical settings were fluences of 3.8 to 4.8 J/cm(2) and a spot size of 3 mm. Follow-ups were conducted via questionnaire with 590 patients who had completed the treatment at least 3 years earlier. @@@ RESULTS Overall, 93.9% of patients achieved complete clearance after an average of 5.2 sessions. All recurrences (0.8%) appeared beyond the previously treated sites. No long-term adverse effects, including hypopigmentation, hyperpigmentation, textural changes, and malignant transformation, were observed. @@@ CONCLUSION The QSAL is a safe and effective modality for treating nevus of Ota. Recurrence was rare and appeared beyond the previously treated sites.

• 出版日期2011-10
• 单位中国医科大学