Residual gastric contents volume does not differ following 4 or 6 h fasting after a light breakfast - a magnetic resonance imaging investigation in healthy non-anaesthetised school-age children

作者：Schmitz A^*; Kellenberger C J; Liamlahi R; Fruehauf M; Klaghofer R; Weiss M

来源：Acta Anaesthesiologica Scandinavica, 2012, 56(5): 589-594.

DOI：10.1111/j.1399-6576.2011.02601.x

Background: While American Society of Anesthesiologists and European Society of Anaesthesiology guidelines recommend 6 h pre-anaesthetic fasting for food and non-clear fluids in children, some institutions allow shorter fasting times of 4 h. Aim of this pilot study was to compare weight-indexed residual gastric contents volumes (GCV(w)) after 4 vs. 6 h after a light breakfast, using magnetic resonance imaging (MRI) in healthy volunteer children not scheduled for anaesthesia.
Methods: Four vs. 6 h (F-4/F-6) of food fasting were simulated in a crossover study. After overnight fasting (baseline), each child ingested a light breakfast (cereal flakes, milk products) on two separate days. Additional clear fluid (7 ml/kg raspberry syrup) was given either after 2 (F-4) or 4 h (F-6), followed by half-hourly MRI acquisition for 2 h. MRI was obtained on a 1.5 Tesla scanner as 5 mm axial images (FIESTA) and volumes were traced manually by one blinded observer. Data are given as median (range) or mean +/- standard deviation.
Results: Eighteen healthy volunteers aged 9.0 (6.8-12.2) years participated. GCV(w) for F-4 and F-6 at baseline was 0.50 +/- 0.27 and 0.76 +/- 0.48 ml/kg (P = 0.07), respectively, GCV(w) after 4 and 6 h was 0.72 +/- 0.85 and 0.47 +/- 0.25 ml/kg (P = 0.88). T-1/2 after syrup intake was 30.8 +/- 12.2 and 28.3 +/- 5.7 min (P = 0.47) for F-4 and F-6, respectively.
Conclusion: Residual gastric contents volumes at a hypothetical anaesthesia start were similar for 4 and 6 h food fasting in healthy volunteer school-age children.

• 出版日期2012-5