An improved transition-metal-free synthesis of aryl alkynyl sulfides via substitution of a halide at an sp-centre

作者：Chowdhury Roomi Mohima; Wilden Jonathan D^*

来源：Organic and Biomolecular Chemistry, 2015, 13(21): 5859-5861.

DOI：10.1039/c5ob00494b

A simple high-yielding preparation of aryl alkynyl sulfides is presented. The reaction of a chloroacetylene with a thiolate salt in the presence of an amine mediator (dimethylamine or N, N'-dimethylethylenediamine) yields the alkynyl sulfides in excellent yields. The alkynyl chloride is easily prepared from the parent alkyne.

• 出版日期2015