alpha-Transducin and alpha-gustducin immunoreactive cells in the stomach of common sole (Solea solea) fed with mussel meal

作者：Mazzoni Maurizio^*; Bonaldo Alessio; Gatta Pier Paolo; Vallorani Claudia; Latorre Rocco; Canova Marco; Clavenzani Paolo

来源：Fish Physiology and Biochemistry, 2015, 41(3): 603-612.

DOI：10.1007/s10695-015-0031-3

• Chemosensory system
• alpha-Transducin
• alpha-Gustducin
• Stomach
• Teleost

Vertebrates perceive a variety of exogenous substances using two main chemosensory systems, taste and olfaction. The taste perception occurs through the interaction of taste receptors associated with specific G protein subunits such as alpha-transducin (G(alpha tran)) and alpha-gustducin (G(alpha gust)). Aquatic vertebrates are also provided with a chemosensory system consisting of solitary chemosensory cells distributed to the oropharynx and skin. In this study, we identified G(alpha tran) and G(alpha gust)-immunoreactive cells intermingled with non-labeled epithelial cells in the gastric mucosa of the common sole. A long-term diet with increasing concentrations of mussel meal in the protein component of a conventional fish meal-based diet induced a dose-dependent increase in the gastric epithelial area and density of G(alpha tran) and G(alpha gust) immunoreactive cells. These findings suggest that taste-related molecules are regulated by changes in diet formulation in common sole aquaculture.

• 出版日期2015-6