Auditory event-related potentials in patients with psychotic illness: A 5-year follow-up

作者：Valkonen Korhonen Minna^*; Tarkka Ina M; Paakkonen Ari; Purhonen Maija

来源：Neurocase, 2012, 18(5): 392-399.

DOI：10.1080/13554794.2011.627337

• Event-related cortical potentials
• Auditory discrimination
• Schizophrenia
• Psychosis
• Medium-term follow-up

The auditory processing is diversely impaired in patients with the first-episode psychosis. During acute phase we previously reported reduced amplitudes in attention-dependent auditory evoked electrical brain potentials but not in those of early automatic components. Here seven first-episode patients at the disease onset and 5 years later were studied and compared to control subjects. At follow-up, also the unattended auditory stimuli elicited reduced amplitudes both in primary sensory component (N100, p = .043) and in automatic deviance detection (N200, p = .013) as compared to acute phase. Patients%26apos; psychopathology had improved, however they still showed alterations in components detecting automatic stimulus classification which may convey persisting tendency for misinterpretation in auditory perception.

• 出版日期2012