Mechanism of formation of distinctive serum proteins adsorbability on diamond like carbon film

作者：Li Bogang^*; Yin Jie; Na Juanjuan; Yin Guangfu

来源：Rare Metal Materials and Engineering, 2007, 36: 61-64.

• diamond like carbon film
• hemocompatibility
• protein adsorption
• hydrogen bond

To clarify the reason causing difference of serum proteins adsorbability on different carbonaceous materials, FT-IR-ATR spectra of human serum albumin (HSA) and human serum fibrinogen. (HFG) before and after adsorbing on diamond like carbon film, (DLC), diamond film (DF) and graphite were analyzed. It has been shown that there are hydrogen bond because of -NH on the inter faces of HSA-DLC, HFG-DF and HFG-graphite. Based on the results, earlier research conclusion that the adsorbability of HSA on DLC is higher than that on DF and graphite, but on DF and graphite the adsorption of HFG takes precedence can be explained rationally.

• 出版日期2007-8
• 单位四川大学