Molecular iodine: A highly efficient catalyst for the regioselective synthesis of novel 1,2,4-triazepines

作者：Kidwai Mazaahir^*; Kukreja Shuchi; Singhal Kavita; Mishra Neeraj Kumar

来源：Indian Journal of Chemistry - Section B: Organic and Medicinal Chemistry , 2016, 55(5): 585-589.

• Dissymmetric-1,3-diarylpropenone
• aminoguanidine-hydrochloride
• molecular iodine
• ethanol
• 1,2,4-triazepines

Various DDPs (Dissymmetric-1,3-diarylpropenones) have been used as efficient building blocks with AGH (aminoguanidine hydrochloride) as polynucleophile rendering NNCN group for the facile synthesis of 1,2,4-triazepines with novel substitution patterns. This one-step methodology employing molecular iodine as catalyst is regioselective, facile and highly efficient.

• 出版日期2016-5