A discrete population of neurons in the lateral amygdala is specifically activated by contextual fear conditioning

作者：Wilson Yvette M; Murphy Mark^*

来源：Learning & Memory, 2009, 16(6): 357-361.

DOI：10.1101/lm.1361509

There is no clear identification of the neurons involved in fear conditioning in the amygdala. To search for these neurons, we have used a genetic approach, the fos-tau-lacZ (FTL) mouse, to map functionally activated expression in neurons following contextual fear conditioning. We have identified a discrete population of neurons in the lateral amygdala that are activated specifically following learning. These neurons have the morphology of principal neurons of the amygdala, and are immunoreactive for glutamate. The highly specific localization of these neurons within the lateral amygdala suggests that these neurons may be a discrete population of neurons involved in fear learning.

• 出版日期2009-6