Multiple molecular simultaneous imaging in a live mouse using semiconductor Compton camera

作者:Motomura Shinji; Kanayama Yousuke; Haba Hiromitsu; Watanabe Yasuyoshi; Enomoto Shuichi*
来源:Journal of Analytical Atomic Spectrometry, 2008, 23(8): 1089-1092.
DOI:10.1039/b802964d

摘要

We have demonstrated the feasibility of semiconductor Compton cameras for multiple molecular imaging in nuclear medicine. The Compton camera used in this work comprises two double-sided orthogonal-strip germanium detectors, and their excellent energy resolution enabled discrimination of the nuclides and accurate determination of the scattering angle for g rays in wide energy range. Three radioactive tracers of (65)ZnCl(2), (85)SrCl(2), and iodinated ((131)I) methylnorcholestenol were injected to a living mouse and were measured simultaneously. Both two- and three- dimensional images of each tracer were obtained by a fixed- angle imaging with a single Compton camera, which reflected the different in vivo behavior of them.

  • 出版日期2008