Absence of association between gallstone and coronary artery calcification

作者:Kwon Chang Hee; Kang Jung Gyu; Lee Hyun Jong; Kim Nan Hee; Sung Joo Wook; Cheong EunSun; Sung Ki Chul*
来源:Atherosclerosis, 2017, 258: 51-55.
DOI:10.1016/j.atherosclerosis.2017.01.035

摘要

Background and aims: Gallstone has been suggested to be associated with cardiovascular disease (CVD). Coronary artery calcification (CAC) is an excellent value to predict future CVD. The aim of this study was to evaluate the association between gallstone and CAC. Methods: Data were analyzed from an occupational cohort of 46,893 subjects (37,557 men and 9336 women) between 2011 and 2014. Participants with cancer or CVD histories or missing data at baseline were excluded from the study. Gallstone was diagnosed by ultrasound-documentation. Multivariate logistic analysis was conducted to examine the relationship between gallstone and CAC. Results: The total population who had gallstone was 1426 (3.1%). In multivariate analysis, odds ratios (OR) for gallstone were not different according to CAC score groups in men and women. In addition, gallstone was not associated with higher OR for CAC in men and women. Conclusions: Gallstone was not associated with CAC in both Korean men and women.

  • 出版日期2017-3