Asymmetric opening of styrene oxide with p-toluidine catalyzed by BINOL polyols and their lithium complexes

作者：Belokon' Yu N^*; Maleev V I; Moskalenko M A; Samoilichenko Yu V; Peregudov A S; Tsaloev A T

来源：Russian Chemical Bulletin, 2013, 62(6): 1371-1376.

DOI：10.1007/s11172-013-0195-x

• asymmetric organic catalysis
• chiral polyols
• alpha-amino alcohols
• kinetic resolution
• oxiranes

Opening of racemic styrene oxide with p-toluidine catalyzed by chiral BINOL-derived polyols proceeded regioselectively mainly with the formation of 2-phenyl-2-(p-tolylamino)-ethanol with low ee values.

• 出版日期2013-6