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摘要
To assess the difference between carotid haemorrhagic plaque and non-haemorrhagic plaque by using diffusion-weighted imaging (DWI) and to evaluate carotid intraplaque haemorrhage (IPH) and intramural hematoma (IMH) of cervical artery dissection with apparent diffusion coefficient (ADC) measurement. @@@ Fifty-one symptomatic patients underwent 3.0-T carotid MR imaging, including conventional sequences, three-dimensional (3D) magnetization-prepared rapid acquisition gradient-echo (MPRAGE) sequence, and DWI. Thirty-nine patients with carotid plaque and eight patients with IMH of cervical artery dissection were finally included. The groups of hemorrhagic plaque, non-hemorrhagic plaque and IMH were divided according to 3D MPRAGE sequence. ADC values of different groups were measured, and t tests were performed. @@@ The mean ADC values of hemorrhagic plaques, non-hemorrhagic plaque and IMH were (1.284 +/- 0.327) x 10(-3)mm(2)/s, (1.766 +/- 0.477) x 10(-3)mm(2)/s, and (0.563 +/- 0.119) x 10(-3)mm(2)/s, respectively. The mean ADC values of hemorrhagic and non-hemorrhagic regions in the hemorrhagic plaque group were (0.985 +/- 0.376) x 10(-3)mm(2)/s and (1.480 +/- 0.465) x 10(-3)mm(2)/s, respectively. The differences between the hemorrhagic plaque and non-hemorrhagic plaque, hemorrhagic region and non-hemorrhagic region in hemorrhagic plaque, and the hemorrhagic region in the hemorrhagic plaque and IMH of artery dissection were significant (P < 0.05). @@@ DWI may be a useful complement to conventional MR imaging for identifying haemorrhage of carotid plaques and differentiate IMHs from IPH. @@@ aEuro cent ADC values of IPH are lower than the plaque without IPH. @@@ aEuro cent DWI might be a useful complement to identify IPH. @@@ aEuro cent IMH may be differentiated from IPH by using DWI.
