Daphnicyclidin M, a new alkaloid from Daphniphyllum paxianum Rosanth

作者:Zhang, Li*; Zhao, GuoHu; Yang, CaiLing; Bai, Lin; Liu, HaiXia
来源:Phytochemistry Letters, 2018, 24: 75-78.
DOI:10.1016/j.phytol.2018.01.002

摘要

A new daphniphyllum alkaloid daphnicyclidin M (1), containing one rare cyclopentadienyl anion, was isolated from the stems and leaves of Daphniphyllum paxianum Rosanth along with five known alkaloids, long-istylumphylline A (2), caldaphnidine A (3), caldaphnidine E (4), daphnilongeranin A (5), and 2-hydroxyyunnandaphnine D (6). The structures were elucidated on the basis of spectroscopic data, and the absolute configuration of 1 was assigned by single-crystal X-ray diffraction crystallography. The isolated compounds were found to have no antibacterial activity against Bacillus subtilis, Escherichia coll., Bacillus cereus, Staphylococcus aureus and Erwinia carotovora.

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