Antihyperlipidemic Compounds from the Fruit of Piper longum L.

作者:Jin Zhuang; Borjihan Gereltu*; Zhao Ruiguo; Sun Zhaorigetu; Hammond Gerald B; Uryu Toshiyuki
来源:Phytotherapy Research, 2009, 23(8): 1194-1196.
DOI:10.1002/ptr.2630

摘要

A bioassay-guided isolation of an ethanol extract of the fruit of Piper longum L. yielded piperlonguminine, piperine and pipernonaline, as the main antihyperlipidemic constituents. They exhibit appreciable antihyperlipidemic activity in vivo, which is comparable to that of the commercial antihyperlipidemic drug, simvastatin.