Assessment of dyspnea and dynamic hyperinflation in male patients with chronic obstructive pulmonary disease during a six minute walk test and an incremental treadmill cardiorespiratory exercise test

作者：Alfonso M^*; Bustamante V; Cebollero P; Anton M; Herrero S; Galdiz J B

来源：Revista Portuguesa de Pneumologia, 2017, 23(5): 266-272.

DOI：10.1016/j.rppnen.2017.04.007

• Treadmill cardiopulmonary exercise test
• 6 minute walk test
• Dynamic hyperinflation
• Chronic obstructive pulmonary disease

The six minute walk test (6MWT) is a standardized test that provides information on exercise capacity in patients with COPD. It is considered a submaximal test in opposition to incremental cardiopulmonary exercise tests (CPET) that provide valuable information on all the systems involved in exercise.
Objectives: 1. To compare the perceptive, physiological responses and degree of dynamic hyperinflation during two exercise tests: the 6MWT and the incremental CPET on a treadmill.
2. To evaluate how dyspnea is related to dynamic hyperinflation (DH) and other functional parameters in both tests.
Methods: 29 stable COPD male patients, age 68 +/- 5.8 years, mean post-bronchodilator FEV1 57 +/- 11%, were recruited. To evaluate dynamic hyperinflation, inspiratory capacity (IC) was measured at rest and upon completing each one of the tests. At the same time, perceived dyspnea and leg discomfort were rated on specific modified Borg scales.
Results: The mean walk distance in 6MWT was 494 +/- 88 m. The Borg scale rating for shortness of breath upon completing the test was 4.7 +/- 2, whilst 2.9 +/- 2 for leg discomfort. IC changed from 2.53 +/- 0.63l before to 2.34 +/- 0.60 l after completion of the test.
In the treadmill CPET, maximal oxygen consumption (VO2 max) was 21.8 +/- 5 mL/kg/min with 6.6 +/- 2 dyspnea and 4.3 +/- 2 leg discomfort on Borg scales. IC changed from 2.17 +/- 0.53l to 1.20 +/- 0.43l.

• 出版日期2017-10