Assessing the impact of public health interventions on the transmission of pandemic H1N1 influenza a virus aboard a Peruvian navy ship

作者：Vera Delphis M^*; Hora Ricardo A; Murillo Anarina; Wong Juan F; Torre Armando J; Wang David; Boulay Darbi; Hancock Kathy; Katz Jacqueline M; Ramos Mariana; Loayza Luis; Quispe Jose; Reaves Erik J; Bausch Daniel G; Chowell Gerardo; Montgomery Joel M

来源：Influenza and Other Respiratory Viruses, 2014, 8(3): 353-359.

DOI：10.1111/irv.12240

• Disease outbreak
• influenza
• military personnel
• Peru
• ships
• transmission

Background Limited data exist on transmission dynamics and effectiveness of control measures for influenza in confined settings. %26lt;br%26gt;Objectives To investigate the transmission dynamics of a 2009 pandemic H1N1 influenza A outbreak aboard a Peruvian Navy ship and quantify the effectiveness of the implemented control measures. %26lt;br%26gt;Methods We used surveillance data and a simple stochastic epidemic model to characterize and evaluate the effectiveness of control interventions implemented during an outbreak of 2009 pandemic H1N1 influenza A aboard a Peruvian Navy ship. %26lt;br%26gt;Results The serological attack rate for the outbreak was 49.1%, with younger cadets and low-ranking officers at greater risk of infection than older, higher-ranking officers. Our transmission model yielded a good fit to the daily time series of new influenza cases by date of symptom onset. We estimated a reduction of 54.4% in the reproduction number during the period of intense control interventions. %26lt;br%26gt;Conclusion Our results indicate that the patient isolation strategy and other control measures put in place during the outbreak reduced the infectiousness of isolated individuals by 86.7%. Our findings support that early implementation of control interventions can limit the spread of influenza epidemics in confined settings.

• 出版日期2014-5