Application of boron as the chromogenic agent in spectrophotometry - I. A novel fading spectro photometric method for the determination of aminomethylbenzoic acid with boric acid

作者：Quan Min Li^*; Tian Tian Zhang

来源：Journal of the Chinese Chemical Society, 2007, 54(4): 983-990.

• boron
• aminomethylbenzoic acid
• chromogenic agent
• fading spectrophotometric method

It is the first time that boron has been used as a chromogenic agent to determine aminomethylbenzoic acid (PAMBA) by the fading spectrophotometric method in this paper. The study indicates that at pH 10.00 the absorbance of PAMBA decreases when boric acid (BA) is added to the solution. A simple, rapid, sensitive and reliable novel method based on the product of PAMBA and BA is obtained. The stoichiometric ratio of the product is 1:2. Beer's law is obeyed in the range of PAMBA concentrations of 0.13 similar to 38.40 1 mu g/mL at a wavelength of 242 nm (epsilon(242) is 8.1 x 10(4) L/mol/cm). The equation of linear regression is A = -0.06635 - 0.02914C (x 10(-5) M), with a linear correlation coefficient of 0.9974. The detection limit is 0. 12 mu g/mL and RSD 0.11%. The method is successfully applied to the determination of PAMBA in pharmaceutical samples, and average recoveries from pharmaceutical samples and urine samples were between 98.4 similar to 102.5%. The other components in these samples do not interfere with the determination by the proposed method.

• 出版日期2007-8
• 单位河南师范大学