Manifestations and clinical impact of pediatric inherited thrombophilia

作者:Klaassen Irene L M; van Ommen C Heleen; Middeldorp Saskia*
来源:Blood, 2015, 125(7): 1073-1077.
DOI:10.1182/blood-2014-05-536060

摘要

The etiology of pediatric venous thromboembolic disease(VTE) ismultifactorial, and in most children, 1 or more clinical risk factors are present. In addition, inherited thrombophilic disorders contribute to the development of pediatric VTE. In this review, the role of inherited thrombophilic disorders in the development of pediatric VTE, as well as the benefits and limitations of thrombophilia testing, will be discussed.

  • 出版日期2015-2-12