An efficient copper-catalyzed formation of highly substituted pyrazoles using molecular oxygen as the oxidant

作者:Suri Mamta; Jousseaume Thierry; Neumann Julia J; Glorius Frank*
来源:Green Chemistry, 2012, 14(8): 2193-2196.
DOI:10.1039/c2gc35476d

摘要

An efficient Cu-catalyzed formation of tetra-substituted pyrazoles is reported. In this atom economic process, readily available enamines and nitriles are reacted by C-C and N-N bond formation. Oxygen has been successfully used as the oxidant, which has important economic and environmental advantages. A broad scope of enamines and nitriles can be utilized in this process.

  • 出版日期2012