Assessment of Left Atrial Function after Percutaneous Closure of Patent Foramen Ovale

作者：Vavuranakis Manolis^*; Kavouras Charalampos; Vlasseros Ioannis; Aggeli Constantina; Felekos Ioannis; Vrachatis Dimitrios A; Stefanadis Christodoulos

来源：Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques, 2013, 30(7): 765-771.

DOI：10.1111/echo.12123

• strain
• strain rate
• structural heart disease
• patent foramen ovale
• echocardiography

Background: The influence of atrial septal occluders in left atrial (LA) function after percutaneous closure of patent foramen ovale (PFO) has not been thoroughly studied. Methods: Twenty-five patients (mean age 40.7 +/- 12 years) undergoing percutaneous PFO closure were enrolled in this study. Transthoracic echocardiogram (TTE) was performed 3 and 6 months before the procedure. Volumetric indices (active emptying fraction: LA AEF, expansion index: LA EI, and passive emptying fraction: LA PEF), strain and strain rate (SR), were calculated during the contractile, reservoir, and conduit LA phases for the lateral, anterior, and inferior LA walls with TTE. Results: After 3 months, a decrease in the SR of the LA anterior wall was observed (from 2.12 +/- 0.22 to 1.66 +/- 0.26, P %26lt; 0.045), while the LA lateral wall strain was found to be increased (from 0.708 +/- 0.15 to 0.783 +/- 0.159, P %26lt; 0.001). Moreover, simultaneously LA AEF was greater compared with baseline (from 31.0 +/- 1.6 to 34.0 +/- 1.6, P %26lt; 0.004). However, all these alterations reversed at 6 months. Conclusions: Segmental LA function is altered transiently after percutaneous PFO closure with a septal occlude. The LA anterior wall SR decreases, while the lateral wall strain increases. The impact of these alterations needs further clarification. (Echocardiography 2013;30:765-771)

• 出版日期2013-8