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摘要
The goal of this study was to assess a new pencil-beam densitometer, the Stratos (Diagnostic Medical Systems, Perols, France). Evaluation of the dosimetry and precision were done together with an in vivo cross-calibration study performed with the fan beam densitometer Discovery A (Hologic, Bedford, MA). The results indicated that the Stratos performed bone mineral density (BMD) measurements with a good precision, low radiation dose, and good agreement with the Discovery A. The air dose, measured by an ionization chamber, was 40 mu Gy. The effective dose was assessed using an anthropomorphic phantom and thermoluminescent detectors resulting in 1.96 and 0.31 mu Sv for a lumbar spine and proximal femur scan, respectively. The average scattered dose rate at a distance of 1 m from the device was 1.06 and 1.21 mu Sv.h(-1) in the lumbar spine and left proximal femur scan mode, respectively. For the precision evaluation, 30 patients underwent 2 lumbar spine and 2 proximal femur scans with repositioning after each scan. The percentage root-mean-square coefficient of variation was 1.22%, 1.38%, 2.11%, and 0.86% for the lumbar spine (L1-L4), lumbar spine (L2-L4), femoral neck, and total hip, respectively. The cross-calibration studies were done on 57 patients (60 +/- 9 yr). Lumbar spine, left neck, and left total hip mean BMD were 3.10% lower and 11.94% and 8.83% higher, respectively, with the Stratos compared with the Discovery A. Cross-calibration equations were calculated with a correlation coefficient of 98% (p < 0.01) for the lumbar spine (L2-L4), 94% (p < 0.01) for the left neck, and 92% (p < 0.01) for the left total hip. After standardizing the Stratos measures using the cross-calibration equations, LIN's concordance correlation coefficient was 0.98, 0.93, and 0.92 for the lumbar spine (L2-L4), left neck, and total hip, respectively.
- 出版日期2011-12
