A transition metal-free tandem process to pyridazinopyrido[3,2-f][1,4]thiazepine-diones via Smiles rearrangement

作者：Niu Xiaoyi; Yang Bingchuan; Li Yanqiu; Fang Shuai; Huang Zixiao; Xie Caixia; Ma Chen^*

来源：Organic and Biomolecular Chemistry, 2013, 11(24): 4102-4108.

DOI：10.1039/c3ob40719e

A transition metal-free methodology for the synthesis of pyridazinopyrido[3,2-f][1,4]thiazepine-diones was studied. The construction of this tricyclic system went through a one-pot coupling/Smiles rearrangement/cyclization process. The high yields of pure products were obtained through simple recrystallization.

• 出版日期2013
• 单位山东大学