Highly responsive hydrogel scaffolds formed by three-dimensional organization of microgel nanoparticles

作者:Cho Eun Chul; Kim Jin Woong; Fernandez Nieves Alberto; Weitz David A*
来源:Nano Letters, 2008, 8(1): 168-172.
DOI:10.1021/nl072346e

摘要

We present a robust and straightforward method for fabricating remarkably responsive hydrogel scaffolds consisting of submicron-sized microgel particles. We demonstrate that the microgel particles assemble either through bridging or depletion interactions to yield a structure that swells or deswells at a macroscopic level in much shorter times as compared to a bulk polymer gel of similar characteristics. This approach offers a new way of fabricating functional hydrogel scaffolds with controllable responsiveness to applied stimuli and excellent loading capability for a wide variety of materials, irrespective of chemistry, size, and shape.

  • 出版日期2008-1