Association of meal frequency with metabolic syndrome in Korean adults: from the Korea National Health and Nutrition Examination Survey (KNHANES)

作者：Jung Chan Hee; Lee Ji Sung; Ahn Hee Jung; Choi Jin Sun; Noh Min Young; Lee Ji Jeung; Lee Eun Young; Lim Jeong Hyun; Lee Young Ran; Yoon So Yoon; Kim Chong Hwa; Cho Dong Hyeok; Choi Young Sik; Choi Kyung Mook^*

来源：Diabetology & Metabolic Syndrome, 2017, 9(1): 77.

DOI：10.1186/s13098-017-0277-2

• Meal frequency
• Metabolic syndrome
• Korean National Health and Nutrition Examination Survey

Background: Although previous studies have established a close relationship between caloric intake and metabolic syndrome, there is limited research exploring the impact of meal frequency adjusted by caloric intake on metabolic syndrome (MetS).
Objective: To evaluate the association of meal frequency and MetS after adjusting for confounding factors including caloric intake in Korean men and women.
Methods: We analyzed the national representative data of a total 12,389 adults (5171 men, 7218 women) from the Korean National Health and Nutrition Examination Survey (KNHANES) 2010-2012. Subjects were categorized as eating 3 meals/day (MF3) or 2 or fewer meals/day (MF <= 2). Daily caloric intake was calculated using CAN-Pro 4.0 (The Korean Nutrition Society, Seoul, Korea).
Results: The prevalence of components of MetS differed significantly according to meal frequency in both men and women. In an unadjusted analysis, the prevalence of MetS in women was significantly higher in the MF3 group than the MF <= 2 group (27.5% vs. 17.8%, P < 0.001), whereas the prevalence of MetS in men did not differ between the MF3 and MF <= 2 groups (24.6% vs. 22.7%, P = 0.281). However, after adjusting for age, caloric intake, smoking status, alcohol consumption, physical activity, income, and education level, men in the MF = 2 group had an increased risk of metabolic syndrome compared to men in the MF3 group (OR = 1.37, 95%, CI = 1.12-1.67). On the other hand, meal frequency did not affect the risk of metabolic syndrome in women after adjusting for confounding factors including caloric intake (OR = 1.09, 95%, CI = 0.90-1.31).
Conclusions: This study suggests that lower meal frequency adjusted for caloric intake, physical activity, age, smoking, alcohol, income, and education may be associated with increased risk of MetS in Korean men.

• 出版日期2017-10-3