A second-generation combined linkage-physical map of the human genome

作者：Matise Tara C^*; Chen Fang; Chen Wenwei; De la Vega Francisco M; Hansen Mark; He Chunsheng; Hyland Fiona C L; Kennedy Giulia C; Kong Xiangyang; Murray Sarah S; Ziegle Janet S; Stewart William C L; Buyske Steven

来源：Genome Research, 2007, 17(12): 1783-1786.

DOI：10.1101/gr.7156307

We have completed a second-generation linkage map that incorporates sequence-based positional information. This new map, the Rutgers Map v. 2, includes 28,121 polymorphic markers with physical positions corroborated by recombination-based data. Sex-averaged and sex-specific linkage map distances, along with confidence intervals, have been estimated for all map intervals. In addition, a regression-based smoothed map is provided that facilitates interpolation of positions of unmapped markers on this map. With nearly twice as many markers as our first-generation map, the Rutgers Map continues to be a unique and comprehensive resource for obtaining genetic map information for large sets of polymorphic markers.

• 出版日期2007-12
• 单位rutgers