Gold catalyzed stereoselective tandem hydroamination-formal aza-Diels-Alder reaction of propargylic amino esters

作者:Fustero Santos*; Bello Paula; Miro Javier; Sanchez Rosello Maria; Maestro Miguel A; Gonzalez Javier; del Pozo Carlos
来源:Chemical communications, 2013, 49(13): 1336-1338.
DOI:10.1039/c2cc37796a

摘要

A gold-catalyzed tandem intramolecular hydroamination-formal aza-Diels-Alder reaction of propargylic amino esters is described. The overall process leads to the formation of a tetracyclic framework as a single diastereoisomer, with the creation of four bonds and five stereocenters.

  • 出版日期2013