A new pyranoxanthone from the stems of Calophyllum membranaceum

作者:Chen, Guang-Ying; Zhu, Guo-Yuan; Han, Chang-Ri*; Zhao, Jun; Song, Xiao-Ping; Fong, Wang-Fun
来源:ARKIVOC, 2008, 249-254.
DOI:10.3998/ark.5550190.0009.d27

摘要

A new pyranoxanthone, membraxanthone A (1) has been isolated from the ethanol extract of the stem of Calophyllum membranaceum, together with three known pyranoxanthones, nigrolineaxanthone W (2), calophinone (3) and caloxanthone I (4), and three known triterpenoids, friedelin (5), canophyllol (6) and canophyllic acid (7). Their structures were elucidated on the basis of chemical evidence and intensive spectroscopic analysis including HRESI-MS, 1D- and 2D-NMR. All of the compounds were isolated from this plant for the first time. These xanthones showed no activities towards human cancer cell lines KB, BC-1 and NCI-4460.