A parietal memory network revealed by multiple MRI methods

作者：Gilmore Adrian W; Nelson Steven M; McDermott Kathleen B

来源：Trends in Cognitive Sciences, 2015, 19(9): 534-543.

DOI：10.1016/j.tics.2015.07.004

• parietal cortex
• memory
• familiarity
• encoding
• retrieval
• functional networks

The manner by which the human brain learns and recognizes stimuli is a matter of ongoing investigation. Through examination of meta-analyses of task-based functional MRI and resting state functional connectivity MRI, we identified a novel network strongly related to learning and memory. Activity within this network at encoding predicts subsequent item memory, and at retrieval differs for recognized and unrecognized items. The direction of activity flips as a function of recent history: from deactivation for novel stimuli to activation for stimuli that are familiar due to recent exposure. We term this network the 'parietal memory network' (PMN) to reflect its broad involvement in human memory processing. We provide a preliminary framework for understanding the key functional properties of the network.

• 出版日期2015-9