Stable TEMPO and ABNO Catalyst Solutions for User-Friendly (bpy)Cu/Nitroxyl-Catalyzed Aerobic Alcohol Oxidation

作者：Steves Janelle E; Stahl Shannon S^*

来源：Journal of Organic Chemistry, 2015, 80(21): 11184-11188.

DOI：10.1021/acs.joc.5b01950

Two solutions, one consisting of bpy/TEMPO/NMI and the other bpy/ABNO/NMI (bpy =2,2'-bipyridyl; TEMPO = 2,2,6,6-tetramethylpiperidine N-oxyl, ABNO = 9-azabicyclo[3.3.1]nonane N-oxyl; NMI = N-methylimidazole), in acetonitrile are shown to have good long-term stability (>= 1 year) under air at 5 degrees C. The solutions may be combined in appropriate quantities with commercially available [Cu(MeCN)(4)]OTf to provide a convenient catalyst system for the aerobic oxidation of primary and secondary alcohols.

• 出版日期2015-11-6