A new chiral ruthenium complex for catalytic asymmetric cyclopropanation

作者：Tang WJ; Hu XQ; Zhang XM^*

来源：Tetrahedron Letters, 2002, 43(16): 3075-3078.

DOI：10.1016/S0040-4039(02)00317-9

A new chiral ruthenium complex 6, featured with an N,O-mixed polydentate ligand, was synthesized and characterized. This ruthenium complex showed high efficiency in catalytic cyclopropanations of alkenes with diazoacetates. High trans/cis selectivity and enantioselectivity (up to 96%) were achieved with the readily accessible ethyl diazoacetate as the reagent.

• 出版日期2002-4-15